Urology focuses on diseases in the urinary-tract system. The field includes conditions treated with both medical and surgical actions. Bladder pain is a symptom causing difficulties and stress in many patients and prevents them from living an ordinary life (1). Navamedic offers products for treatment in the area of urology, with a strong focus on management of chronic cystitis, such as interstitial cystitis/Bladder Pain Syndrome, or chronic urinary tract infections. These conditions cause bladder pain, urinary urgency and frequency, and to some patients also incontinence (1).
1.Nordling, Van Ophoven. (2008) Intravesical glucosaminoglucan replenishment with chondroitin Sulphate in chronic forms of cysticitis. A drug research. (Arzneiittel forschung)
Gepan Instill is an effective therapy for the treatment for chronic forms of cystitis, such as interstitial cystitis, radiation cystitis, chronic recurrent cystitis and overactive bladder. Gepan instill is a pH-neutral, sterile solution which contains chondroitin sulphate (0.2%), a natural component of the protective layer of the bladder.
Elmiron is a medicine used to treat adults with bladder pain syndrome, a condition of the bladder which causes pain in the pelvic area and a frequent, urgent need to pass urine.
Elmiron is used in patients with moderate to severe pain and who have small bleeds or lesions (sores) in the bladder wall. It contains the active substance pentosan polysulfate sodium.
Elmiron is available as 100-mg capsules and can only be obtained with a prescription. The recommended dose is one capsule taken three times a day. Patients should be assessed every six months and treatment should be stopped if no improvement is seen.
The way the active substance in Elmiron, pentosan polysulfate sodium, works is not fully understood but it passes into the urine and is thought to attach to and help repair the protective layer of mucus lining the bladder, which is deficient in patients with bladder pain syndrome. This reinforcement of the protective layer may reduce inflammation and bladder pain.
Because pentosan polysulfate sodium is a well-known substance, and its use in bladder pain syndrome is well established, the company for Elmiron presented data from the scientific literature. A review of 4 main studies from the literature showed that pentosan polysulfate sodium is effective at reducing symptoms, such as pain and the urge to pass urine frequently.
For extended Product information, please visit: www.ema.europa.eu/en/medicines/human/EPAR/elmiron